KDELR2 ELISA kits are immunoassay tools for the measurement of the protein KDEL endoplasmic reticulum protein retention receptor 2, which is encoded by the KDELR2 gene in humans. Functionally, this protein is reported to be a membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi. The canonical protein structure is reported to have an amino acid length of 212 residues, a mass of 24.4 kDa, and is a member of the ERD2 protein family. It is known to be localized in the ER, golgi, and cytoplasmic vesicles. As many as 2 protein isoforms have been reported. The KDELR2 gene has been associated with the disease, Osteogenesis imperfecta. Other alias names for this target include ELP1, ERD2.2, OI21, ER lumen protein-retaining receptor 2, (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, and ELP-1.
The detection range for different KDELR2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.