The following Neurofilament heavy chain ELISA kits are useful research tools for the measurement of neurofilament heavy chain in biological samples. In humans this protein is encoded by the NEFH gene. This protein is known to be involved in neurite outgrowth by regulating cell-cell adhesion via the N-cadherin signaling pathway. The canonical protein structure is reported to have an amino acid sequence of 1026 residues and a mass of 112.5 kDa. Its subcellular location is known to be in the cytoplasm. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Amyotrophic lateral sclerosis. This protein may also be known as NFH, neurofilament heavy polypeptide, 200 kDa neurofilament protein, NF-H, neurofilament triplet H protein, and CMT2CC.
Some Neurofilament heavy chain ELISA kits can detect targets at levels as low as 15.6 pg/mL and as high as 150 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.