The following cell cycle and apoptosis regulator 2 ELISA kits are useful research tools for the measurement of cell cycle and apoptosis regulator 2 in biological samples. In humans this protein is encoded by the CCAR2 gene. This protein is an important component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. The canonical protein structure is reported to have an amino acid sequence of 923 residues and a mass of 102.9 kDa. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally sumoylated, acetylated and phosphorylated. This protein may also be known as cell division cycle and apoptosis regulator protein 2, deleted in breast cancer 1, and cell cycle and apoptosis regulator protein 2.
There are cell cycle and apoptosis regulator 2 ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.