Anti-LRRC8C antibodies are used in the immunodetection of the protein leucine rich repeat containing 8 VRAC subunit C. In humans, the canonical protein has a reported length of 803 amino acid residues and a mass of 92.5 kDa. Its subcellular localization is in the ER and cell membrane. It is reported to be expressed at highest levels in skeletal muscle, and at moderate levels in the heart, lung and peripheral blood leukocytes. A member of the LRRC8 protein family, LRRC8C is reported to be a non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. Synonyms for this target antigen include factor for adipocyte differentiation 158, hypothetical protein AD158, leucine rich repeat containing 8 family member C, and volume-regulated anion channel subunit LRRC8C. LRRC8C gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. ELISA, Western Blot, Immunofluorescence, and Immunohistochemistry are common applications for LRRC8C antibodies.