Anti-SPRED1 antibodies are used in the immunodetection of the protein sprouty related EVH1 domain containing 1. In humans, the canonical protein has a reported length of 444 amino acid residues and a mass of 50.5 kDa. Its subcellular localization is in the nucleus and cell membrane. It is reported to be weakly expressed in embryonic cell line HEK293. SPRED1 is known to be involved with the regulation of angiogenesis and the regulation of cell differentiation. Post-translational modifications have been described, including ubiquitination, palmitoylation and phosphorylation. The SPRED1 gene has been associated with the disease, Legius syndrome. Synonyms for this target antigen include protein phosphatase 1, regulatory subunit 147, suppressor of Ras/MAPK activation, and sprouty-related, EVH1 domain-containing protein 1. SPRED1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SPRED1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.