Anti-FRMD8 antibodies are used in the immunodetection of the protein FERM domain containing 8. In humans, the canonical protein has a reported length of 464 amino acid residues and a mass of 51.2 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is found to be widely expressed, with high expression in the heart and spleen. FRMD8 is reported to promote the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. Synonyms for this target antigen include band4.1 inhibitor LRP interactor, bili, iRhom Tail-Associated Protein, and FERM domain-containing protein 8. FRMD8 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some FRMD8 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.