Anti-FGD6 antibodies are used in the immunodetection of the protein FYVE, RhoGEF and PH domain containing 6. In humans, the canonical protein has a reported length of 1430 amino acid residues and a mass of 160.8 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. FGD6 is believed to activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Synonyms for this target antigen include FYVE, RhoGEF and PH domain-containing protein 6 and zinc finger FYVE domain-containing protein 24. FGD6 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Immunohistochemistry is the most common application for the FGD6 antibodies listed below. ELISA and Western Blot are also common applications.