Anti-PTPRU antibodies are used in the immunodetection of the protein protein tyrosine phosphatase receptor type U. In humans, the canonical protein has a reported length of 1446 amino acid residues and a mass of 162.4 kDa. Its subcellular localization is in the cell membrane. Up to 4 different isoforms have been reported for this protein. It is notably expressed in the brain, pancreas, and skeletal muscle; less in colon, kidney, liver, stomach, and uterus; not expressed in the placenta and spleen. A member of the Protein-tyrosine phosphatase protein family, PTPRU is reported to be a tyrosine-protein phosphatase, which dephosphorylates CTNNB1. Synonyms for this target antigen include PCP-2, PTP, PTP-J, PTP-PI, PTP-RO, PTPPSI, PTPRO, and FMI. PTPRU gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some PTPRU antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.