Anti-NDUFV2 antibodies are used in the immunodetection of the protein NADH:ubiquinone oxidoreductase core subunit V2. In humans, the canonical protein has a reported length of 249 amino acid residues and a mass of 27.4 kDa. Its subcellular localization is in the mitochondria. It is notably widely expressed in many tissue types. A member of the Complex I 24 kDa subunit protein family, NDUFV2 is reported to be a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
The NDUFV2 marker can be used to identify T Follicular Helper Cells.* Synonyms for this target antigen include MC1DN7, NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial, NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa, NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial, and CI-24k. NDUFV2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4