Anti-SOX18 antibodies are used in the immunodetection of the protein SRY-box transcription factor 18. In humans, the canonical protein has a reported length of 384 amino acid residues and a mass of 40.9 kDa. Its subcellular localization is in the nucleus. It is notably expressed in fetal lung, placenta, skeletal muscle, liver, kidney, spleen, prostate, ovary, msosmall intestine and colon. SOX18 is reported to be a transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis. Synonyms for this target antigen include HLTS, transcription factor SOX-18, SRY (sex determining region Y)-box 18, SRY-box 18, and HLTRS. SOX18 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of SOX18 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.