Anti-SPDL1 antibodies are used in the immunodetection of the protein spindle apparatus coiled-coil protein 1. In humans, the canonical protein has a reported length of 605 amino acid residues and a mass of 70.2 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Spindly protein family, SPDL1 is known to be required for the localization of dynein and dynactin to the mitotic kintochore. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include protein Spindly, arsenite-related gene 1 protein, coiled-coil domain-containing protein 99, rhabdomyosarcoma antigen MU-RMS-40.4A, rrhabdomyosarcoma antigen protein MU-RMS-40.4A, and CCDC99. SPDL1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SPDL1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.