Anti-MISP antibodies are used in the immunodetection of the protein mitotic spindle positioning. In humans, the canonical protein has a reported length of 679 amino acid residues and a mass of 75.4 kDa. Its subcellular localization is in the cell junctions and cytoplasm. It is notably expressed in the rectum, gallbladder, duodenum, colon, and appendix. A member of the MISP protein family, MISP is reported to play a role in mitotic spindle orientation and mitotic progression. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include caprice, mitotic spindle positioning protein, and mitotic interactor and substrate of PLK1. MISP gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chicken species. Some MISP antibodies may have been used in research and have associated citations. Western Blot, Immunofluorescence, and Immunohistochemistry are common applications for these antibodies.