Anti-LDLRAD4 antibodies are used in the immunodetection of the protein low density lipoprotein receptor class A domain containing 4. In humans, the canonical protein has a reported length of 306 amino acid residues and a mass of 33.9 kDa. Its subcellular localization is in the endosome. Up to 8 different isoforms have been reported for this protein. It is reported to be expressed in lymphocytes. A member of the PMEPA1 protein family, LDLRAD4 is known to function as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. Synonyms for this target antigen include low-density lipoprotein receptor class A domain-containing protein 4, clone 22, and C18orf1. LDLRAD4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some LDLRAD4 antibodies may have been used in research and have associated citations. Immunofluorescence is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.