Anti-ARHGEF28 antibodies are used in the immunodetection of the protein Rho guanine nucleotide exchange factor 28. In humans, the canonical protein has a reported length of 1705 amino acid residues and a mass of 191.9 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 6 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the cerebral cortex and hippocampus. ARHGEF28 is known to function as a RHOA-specific guanine nucleotide exchange factor regulating signaling pathways downstream of integrins and growth factor receptors. Synonyms for this target antigen include Rho guanine nucleotide exchange factor (GEF) 28, Rho interacting protein 2, rho-guanine nucleotide exchange factor, and 190 kDa guanine nucleotide exchange factor. ARHGEF28 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ARHGEF28 antibodies have been mentioned in research publications and have associated citations. Immunocytochemistry is a widely used application for these antibodies. ELISA, Western Blot, Immunofluorescence, and Immunohistochemistry are also common applications.