PRMT5 is a symbol for the gene, Protein arginine methyltransferase 5, in humans. Other names include: Protein arginine N-methyltransferase 5; Histone-arginine N-methyltransferase PRMT5; Jak-binding protein 1; Shk1 kinase-binding protein 1 homolog; SKB1 homolog; SKB1Hs; 72 kDa ICln-binding protein; Protein arginine N-methyltransferase 5 ; HRMT1L5; IBP72; JBP1; SKB1. The encoded protein is an enzyme with an amino acid length of 637 and a mass of 72.7 kDa. Other isoforms may exist. PRMT5 is a member of the Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family. This gene shares homology with other species, including: Mouse, Fly, Rat, Arabidopsis, Zebrafish, Frog.