Anti-WIF1 antibodies are used in the immunodetection of the protein WNT inhibitory factor 1. In humans, the canonical protein has a reported length of 379 amino acid residues and a mass of 41.5 kDa. It has been described to be a secreted protein. WIF1 is known to bind to WNT proteins and inhibits their activities. Post-translational modifications have been described, including glycosylation. The WIF1 marker can be used to identify Gray Matter Astrocytes and Gray Matter Interneurons.* WIF1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4