Anti-PRPS2 antibodies are used in the immunodetection of the protein phosphoribosyl pyrophosphate synthetase 2. In humans, the canonical protein has a reported length of 318 amino acid residues and a mass of 34.8 kDa. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of a the Ribose-phosphate pyrophosphokinase protein family, PRPS2 is known to catalyze the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. Synonyms for this target antigen include ribose-phosphate pyrophosphokinase 2, PPRibP synthetase, PRS-II, phosphoribosyl pyrophosphate synthase II, ribose-phosphate diphosphokinase 2, and PRSII.