Anti-ZNRF2 antibodies are used in the immunodetection of the protein zinc and ring finger 2. In humans, the canonical protein has a reported length of 242 amino acid residues and a mass of 24.1 kDa. Its subcellular localization is in the endosome, lysosomes, and cell membrane. It is reported to be highly expressed in the brain, with higher expression during development than in adult. ZNRF2 is believed to play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. Synonyms for this target antigen include RING finger protein 202, RING-type E3 ubiquitin transferase ZNRF2, protein Ells2, zinc and ring finger 2, E3 ubiquitin protein ligase, and E3 ubiquitin-protein ligase ZNRF2. ZNRF2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ZNRF2 antibodies have been mentioned in research publications and have associated citations. Immunofluorescence is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.