Anti-USP45 antibodies are used in the immunodetection of the protein ubiquitin specific peptidase 45. In humans, the canonical protein has a reported length of 814 amino acid residues and a mass of 91.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the Peptidase C19 protein family, USP45 is known to catalyze the deubiquitination of SPDL1. The USP45 gene has been associated with the disease, Leber congenital amaurosis. Synonyms for this target antigen include deubiquitinating enzyme 45, ubiquitin specific protease 45, ubiquitin thioesterase 45, ubiquitin thiolesterase 45, ubiquitin-specific-processing protease 45, and ubiquitin carboxyl-terminal hydrolase 45. USP45 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. ELISA is the most common application for the USP45 antibodies listed below. Western Blot and Immunohistochemistry are also common applications.