Anti-PRSS16 antibodies are used in the immunodetection of the protein serine protease 16. In humans, the canonical protein has a reported length of 514 amino acid residues and a mass of 55 kDa. Its subcellular localization is in the cytoplasmic vesicles. It is reported to be highly expressed in cortical thymic epithelial cells. A member of the Peptidase S28 protein family, PRSS16 is a reported protease that may play a role in T-cell development. Post-translational modifications have been described, including glycosylation.
The PRSS16 marker can be used to identify Cortical Thymic Epithelial Cells.* Synonyms for this target antigen include thymus-specific serine protease, protease, serine 16, protease, serine, 16 (thymus), thymus specific serine peptidase, and TSSP. PRSS16 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. Some PRSS16 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4