Anti-SYT2 antibodies are used in the immunodetection of the protein synaptotagmin 2. In humans, the canonical protein has a reported length of 419 amino acid residues and a mass of 46.9 kDa. Its subcellular localization is in the cytoplasmic vesicles. It is noted to be expressed at the neuromuscular junction. A member of the Synaptotagmin protein family, SYT2 is known to be involved with cell differentiation. Post-translational modifications have been described, including glycosylation. The SYT2 marker can be used to identify Midbrain-Derived Inhibitory Neurons.* Synonyms for this target antigen include synaptotagmin II. SYT2 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. A number of Syt2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4