Anti-CLPB antibodies are used in the immunodetection of the protein ClpB family mitochondrial disaggregase. In humans, the canonical protein has a reported length of 707 amino acid residues and a mass of 78.7 kDa. Its subcellular localization is in the mitochondria. Alternative splicing is reported to yield 5 different isoforms for this protein. It is widely expressed across many tissue types. A member of a the ClpA/ClpB protein family, CLPB is known to function as a regulatory ATPase and participates in secretion/protein trafficking process. Post-translational modifications have been described, including protein cleavage. Synonyms for this target antigen include ClpB caseinolytic peptidase B homolog, ClpB homolog, mitochondrial AAA ATPase chaperonin, ankyrin-repeat containing bacterial clp fusion, and caseinolytic peptidase B protein homolog.