Anti-KLHL22 antibodies are used in the immunodetection of the protein kelch like family member 22. In humans, the canonical protein has a reported length of 634 amino acid residues and a mass of 71.7 kDa. Its subcellular localization is in the nucleus, lysosomes and cytoplasm. Up to 2 different isoforms have been reported for this protein. KLHL22 is reported to be a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. Synonyms for this target antigen include kelch-like protein 22 and kelch-like 22. KLHL22 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some KLHL22 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.