Anti-ESPN antibodies are used in the immunodetection of the protein espin. In humans, the canonical protein has a reported length of 854 amino acid residues and a mass of 91.7 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the colon and duodenum. The ESPN gene has been associated with the disease, Deafness. Synonyms for this target antigen include autosomal recessive deafness type 36 protein and ectoplasmic specialization protein. ESPN gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ESPN antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.