Anti-ASB10 antibodies are used in the immunodetection of the protein ankyrin repeat and SOCS box containing 10. In humans, the canonical protein has a reported length of 467 amino acid residues and a mass of 50.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably expressed in the eye. A member of the Ankyrin SOCS box (ASB) protein family, ASB10 is believed to be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The ASB10 gene has been associated with the disease, Glaucoma. Synonyms for this target antigen include ankyrin repeat and SOCS box protein 10. ASB10 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. ELISA and Western Blot are common applications for ASB10 antibodies.