Anti-FAM120B antibodies are used in the immunodetection of the protein family with sequence similarity 120B. In humans, the canonical protein has a reported length of 910 amino acid residues and a mass of 103.8 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. It is widely expressed across many tissue types. A member of a the Constitutive coactivator of PPAR-gamma protein family, FAM120B is known to function as a transactivator of PPARG and ESR1. Synonyms for this target antigen include PPARG constitutive coactivator 1, PPARgamma constitutive coactivator 1, constitutive coactivator of PPAR-gamma, and constitutive coactivator of peroxisome proliferator-activated receptor gamma.