Anti-GPHA2 antibodies are used in the immunodetection of the protein glycoprotein hormone subunit alpha 2. In humans, the canonical protein has a reported length of 129 amino acid residues and a mass of 14.2 kDa. It has been described to be a secreted protein. A member of the Glycoprotein hormones subunit alpha protein family, GPHA2 is known to function as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include cysteine knot protein, glycoprotein alpha 2, glycoprotein hormone alpha 2, putative secreted protein Zsig51, thyrostimulin subunit alpha, and glycoprotein hormone alpha-2. GPHA2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. Some GPHA2 antibodies may have been used in research and have associated citations. ELISA is a widely used application for these antibodies. In addition, Western Blot is also a common application.