Anti-AK3 antibodies are used in the immunodetection of the protein adenylate kinase 3. In humans, the canonical protein has a reported length of 227 amino acid residues and a mass of 25.6 kDa. Its subcellular localization is in the mitochondria. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in the heart, skeletal muscle and liver, moderately expressed in the pancreas and kidney, and weakly expressed in the placenta, brain and lung. A member of the Adenylate kinase protein family, AK3 is known to be involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Synonyms for this target antigen include AK6, AKL3L1, FIX, GTP:AMP phosphotransferase AK3, mitochondrial, and AK3L1. AK3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some AK3 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Flow Cytometry and Immunohistochemistry are also common applications.