Anti-ARHGEF2 antibodies are used in the immunodetection of the protein Rho/Rac guanine nucleotide exchange factor 2. In humans, the canonical protein has a reported length of 986 amino acid residues and a mass of 111.5 kDa. Its subcellular localization is in the cytoplasmic vesicles, Golgi, and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the bone marrow and lymph node. ARHGEF2 is known to be involved with the cell cycle and TNF-mediated cellular signaling pathways. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include GEF-H1, GEFH1, LFP40, Lfc, NEDMHM, P40, rho guanine nucleotide exchange factor 2, and GEF. ARHGEF2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 70 citations in the literature describe the use of ARHGEF2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.