Anti-TBC1D2B antibodies are used in the immunodetection of the protein TBC1 domain family member 2B. In humans, the canonical protein has a reported length of 963 amino acid residues and a mass of 109.9 kDa. Its subcellular localization is in the endosome. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. TBC1D2B is reported to be a GTPase-activating protein that plays a role in the early steps of endocytosis. The TBC1D2B gene has been associated with the disease, Neurodevelopmental disorder with seizures and gingival overgrowth. Synonyms for this target antigen include NEDSGO. TBC1D2B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some TBC1D2B antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.