Anti-ZAP3 antibodies enable researchers to detect and measure the ZAP3 antigen in biological samples. This target is a reported synonym of the YLPM1 gene, which encodes YLP motif containing 1. This protein is reported to play a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation. The human version of ZAP3 has a canonical amino acid length of 2146 residues and a protein mass of 241.6 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the nucleus of cells.