Anti-NMBR antibodies are used in the immunodetection of the protein neuromedin B receptor. In humans, the canonical protein has a reported length of 390 amino acid residues and a mass of 43.4 kDa. Its subcellular localization is in the cell membrane. It is reported to be expressed in epididymis. A member of the G-protein coupled receptor 1 protein family, NMBR is a known receptor for neuromedin-B. Post-translational modifications have been described, including glycosylation.
The NMBR marker can be used to identify Gray Matter Interneurons.* Synonyms for this target antigen include BB1R, BRS1, bombesin receptor 1, epididymis secretory sperm binding protein Li 185a, epididymis tissue protein Li 185a, and BB1. NMBR gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Some NMBR antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4