SSB3, or SplA/ryanodine receptor domain and SOCS box containing 3, is a human gene encoded by SPSB3. It may also be known as: SPRY domain-containing SOCS box protein 3; SSB-3; C16orf31. The encoded protein has an amino acid length of 355 and a mass of 39.4 kDa. Other isoforms may exist. SSB3 is a member of the SPSB family. Homologs of this gene exist in other organisms, including: Mouse, Rat, Frog, Chicken.