Anti-SPGP antibodies are used in antigen-specific immunodetection in biological samples. The target SPGP is a known alias name of the protein ATP binding cassette subfamily B member 11, encoded by the ABCB11 gene in humans. This 1321-amino acid residue protein is known to catalyze the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner. It is localized to the cell membrane of the cell and features N-glycosylated and ubiquitinated post-translational modifications. In terms of tissue expression, it is noted to be expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ. Other synonyms for SPGP include ABC16, BRIC2, and BSEP. Some SPGP antibodies may have been used in research and have associated citations. Indicated applications for the antibodies listed below include ELISA, Western Blot, Immunocytochemistry, and Immunohistochemistry.