Anti-CCNF antibodies are used in the immunodetection of the protein cyclin F. In humans, the canonical protein has a reported length of 786 amino acid residues and a mass of 87.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is found to be widely expressed, with expression detected in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. A member of the Cyclin protein family, CCNF is reported to be a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Synonyms for this target antigen include FBXO1, FTDALS5, F-box only protein 1, G2/mitotic-specific cyclin-F, and FBX1. CCNF gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. A number of CCNF antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.