Anti-SHO antibodies are used in antigen-specific immunodetection in biological samples. The target SHO is a known alias name of the protein shadow of prion protein, encoded by the SPRN gene in humans. This 151-amino acid residue protein is reported to be a prion-like protein that has PrP(C)-like neuroprotective activity. It is localized to the cell membrane of the cell and features N-glycosylated post-translational modifications. In terms of tissue expression, it is reported to be mainly expressed in the brain. Indicated applications for SHO antibodies listed below include ELISA, Western Blot, and Immunohistochemistry.