Anti-RECQL3 antibodies are protein reagents that detect specific antigens. The RECQL3 antigen is another term for the human protein WRN RecQ like helicase, encoded by the WRN gene. The protein is reported to be a multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Canonically, it has an amino acid length of 1432 residues and a mass of 162.5 kilodaltons. Its subcellular localization is in the nucleus and it is expressed in many tissues, such as the bronchus, vagina, and adrenal gland. The RECQL3 protein is a member of the Helicase protein family.