Anti-POLR2M antibodies are used in the immunodetection of the protein RNA polymerase II subunit M. In humans, the canonical protein has a reported length of 368 amino acid residues and a mass of 41.7 kDa. Its subcellular localization is in the nucleus. Up to 6 different isoforms have been reported for this protein. It is notably expressed in adult an fetal brain. A member of the GRINL1 protein family, POLR2M is known to be involved with intracellular signal transduction. Synonyms for this target antigen include GRINL1A downstream protein Gdown4, glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A, polymerase (RNA) II (DNA directed) polypeptide M, polymerase (RNA) II subunit M, and protein GRINL1A. POLR2M gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. Western Blot is a widely used application for the POLR2M antibodies listed below. In addition, ELISA is also a common application.