Anti-RAPGAP antibodies are protein reagents that detect specific antigens. The RAPGAP antigen is another term for the human protein RAP1 GTPase activating protein, encoded by the RAP1GAP gene. The protein is known to be a GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. Canonically, it has an amino acid length of 663 residues and a mass of 73.4 kilodaltons. Its subcellular localization is in the Golgi and membrane and it is widely expressed in many tissue types. Other alias names for RAPGAP include RAP1GA1, RAP1GAP1, and RAP1GAPII.