Anti-JC8.6 antibodies enable researchers to detect and measure the JC8.6 antigen in biological samples. This target is a reported synonym of the LIN54 gene, which encodes lin-54 DREAM MuvB core complex component. This protein is known to function in the cell cycle and the regulation of transcription, among other biological roles. The human version of JC8.6 has a canonical amino acid length of 749 residues and a protein mass of 79.5 kilodaltons, although 5 isoforms have been identified. It is reported to be localized in the nucleus of cells and widely expressed in many tissue types. JC8.6 is a member of the Lin-54 protein family.