Anti-HNP-3 antibodies enable researchers to detect and measure the HNP-3 antigen in biological samples. This target is a reported synonym of the DEFA3 gene, which encodes defensin alpha 3. This protein is known to function in the cellular response to lipopolysaccharides and viral immune response, among other biological roles. The human version of HNP-3 has a canonical amino acid length of 94 residues and a protein mass of 10.2 kilodaltons. It is reported to be a secreted protein that is notably expressed in the bone marrow and spleen. Other names for this target antigen include DEF3 and HNP-3.