Anti-HREP antibodies enable researchers to detect and measure the HREP antigen in biological samples. This target is a reported synonym of the FBXW10 gene, which encodes F-box and WD repeat domain containing 10. This protein is a suspected substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The human version of HREP has a canonical amino acid length of 1052 residues and a protein mass of 119.8 kilodaltons, although 4 isoforms have been identified.