Anti-HOFI antibodies enable researchers to detect and measure the HOFI antigen in biological samples. This target is a reported synonym of the SH3PXD2B gene, which encodes SH3 and PX domains 2B. This protein is known to function in adipose tissue development and bone development, among other biological roles. The human version of HOFI has a canonical amino acid length of 911 residues and a protein mass of 101.6 kilodaltons. It is reported to be localized in the cytoplasm of cells and widely expressed in many tissue types. HOFI is a member of the SH3PXD2 protein family.