Anti-ECA2 antibodies are protein reagents that detect specific antigens. The ECA2 antigen is another term for the human protein chloride voltage-gated channel 2, encoded by the CLCN2 gene. The protein is known to function in acinar cell differentiation and lung development, among other biological roles. Canonically, it has an amino acid length of 898 residues and a mass of 98.5 kilodaltons. Its subcellular localization is in the cell membrane and it is ubiquitously expressed across many tissue types. The ECA2 protein is a member of the Chloride channel (TC 2.A.49) protein family.