Anti-HMGN3 antibodies are used in the immunodetection of the protein high mobility group nucleosomal binding domain 3. In humans, the canonical protein has a reported length of 99 amino acid residues and a mass of 10.7 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in the kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate and uterus. A member of the HMGN protein family, HMGN3 is known to bind to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Synonyms for this target antigen include PNAS-25, TRIP7, high mobility group nucleosome-binding domain-containing protein 3, TR-interacting protein 7, thyroid hormone receptor interacting protein 7, and PNAS-24. HMGN3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the HMGN3 antibodies listed below. ELISA and Immunohistochemistry are also common applications.