CFIM25 is an alias for the gene, Nudix hydrolase 21, in humans. Other names include: Cleavage and polyadenylation specificity factor subunit 5; Cleavage and polyadenylation specificity factor 25 kDa subunit; CFIm25; CPSF 25 kDa subunit; Nucleoside diphosphate-linked moiety X motif 21; Nudix motif 21; Pre-mRNA cleavage factor Im 25 kDa subunit; cleavage factor Im complex 25 kDa subunit; CPSF5; nudix (nucleoside diphosphate linked moiety X)-type motif 21. The encoded protein has an amino acid length of 227 and a mass of 26.2 kDa. Other isoforms may exist. CFIM25 is a member of the Nudix hydrolase family, CPSF5 subfamily. This gene shares homology with other species, including: Mouse, Rat, Arabidopsis, Frog, Chicken.