Anti-CENPA antibodies are used in the immunodetection of the protein centromere protein A. In humans, the canonical protein has a reported length of 140 amino acid residues and a mass of 16 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the cervix, tonsil, and bone marrow. A member of the Histone H3 protein family, CENPA is known to be involved with cell division. Synonyms for this target antigen include histone H3-like centromeric protein A, centromere autoantigen A, centromere protein A, 17kDa, centromere-specific histone, and CenH3. CENPA gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 180 citations in the literature describe the use of CENPA antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.