Anti-AGAS antibodies are used in antigen-specific immunodetection in biological samples. The target AGAS is a known alias name of the protein N-acetylglutamate synthase, encoded by the NAGS gene in humans. This 534-amino acid residue protein is reported to play a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity. It is localized to the mitochondria of the cell. In terms of tissue expression, it is reported to be highly expressed in the adult liver, kidney and small intestine. Indicated applications for AGAS antibodies listed below include ELISA and Western Blot.