Anti-G-substrate antibodies enable researchers to detect and measure the G-substrate antigen in biological samples. This target is a reported synonym of the PPP1R17 gene, which encodes protein phosphatase 1 regulatory subunit 17. This protein is known to function in nervous system development and intracellular signal transduction, among other biological roles. The human version of G-substrate has a canonical amino acid length of 155 residues and a protein mass of 17.9 kilodaltons, although 2 isoforms have been identified. It is reported to be notably expressed in the testis, hypothalamus, and cerebellum. Other names for this target antigen include C7orf16, GSBS, and G-substrate.