Anti-ROC2 antibodies are used in antigen-specific immunodetection in biological samples. The target ROC2 is a known alias name of the protein ring finger protein 7, encoded by the RNF7 gene in humans. This 113-amino acid residue protein is a suspected component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. It is localized to the nucleus and cytoplasm of the cell and features phosphorylated post-translational modifications. In terms of tissue expression, it is found to be expressed in the heart, liver, skeletal muscle and pancreas.